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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPRU
All Species:
17.88
Human Site:
Y782
Identified Species:
43.7
UniProt:
Q92729
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92729
NP_005695.3
1446
162423
Y782
D
H
Y
A
Y
S
Y
Y
P
K
P
V
N
M
T
Chimpanzee
Pan troglodytes
XP_513263
1483
166127
Y819
D
H
Y
A
Y
S
Y
Y
P
K
P
V
N
M
T
Rhesus Macaque
Macaca mulatta
XP_001115805
1350
152055
R712
H
M
M
S
A
V
D
R
S
F
T
D
Q
S
T
Dog
Lupus familis
XP_852271
1446
162532
Y782
D
H
Y
A
Y
S
Y
Y
P
K
P
V
N
M
T
Cat
Felis silvestris
Mouse
Mus musculus
B1AUH1
1446
162475
Y782
D
R
Y
A
Y
S
Y
Y
P
K
P
V
N
M
T
Rat
Rattus norvegicus
Q64604
1898
211475
S1231
D
Q
K
R
Y
A
S
S
P
Y
S
D
E
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6YI48
1434
161661
K771
A
I
I
V
V
I
R
K
G
K
P
V
N
M
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B3DK56
1444
162642
P782
Y
Y
S
Y
S
Y
Y
P
R
K
P
G
N
M
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16621
2029
229038
T1178
I
N
E
L
S
P
F
T
T
Y
N
V
N
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9BMN8
2200
246601
S1535
G
R
H
P
R
H
G
S
I
T
K
V
A
L
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
92.6
97
N.A.
95.3
25.6
N.A.
N.A.
84.9
N.A.
75.1
N.A.
24.5
N.A.
23.4
N.A.
Protein Similarity:
100
96.7
92.8
98.5
N.A.
97.3
41.6
N.A.
N.A.
92.5
N.A.
85.8
N.A.
41
N.A.
36.8
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
93.3
20
N.A.
N.A.
40
N.A.
33.3
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
33.3
N.A.
N.A.
40
N.A.
40
N.A.
40
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
40
10
10
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
0
10
0
0
0
0
20
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
10
0
10
0
0
10
0
0
0
% G
% His:
10
30
10
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
10
0
0
10
0
0
10
0
0
0
0
10
0
% I
% Lys:
0
0
10
0
0
0
0
10
0
60
10
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% L
% Met:
0
10
10
0
0
0
0
0
0
0
0
0
0
60
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
10
0
70
0
10
% N
% Pro:
0
0
0
10
0
10
0
10
50
0
60
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
20
0
10
10
0
10
10
10
0
0
0
0
0
0
% R
% Ser:
0
0
10
10
20
40
10
20
10
0
10
0
0
10
10
% S
% Thr:
0
0
0
0
0
0
0
10
10
10
10
0
0
0
70
% T
% Val:
0
0
0
10
10
10
0
0
0
0
0
70
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
40
10
50
10
50
40
0
20
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _